The interaction between APOE‐e4 gene and paid work for women in predicting ADAS 13 scores

Background The associated risk of Alzheimer’s disease linked to the APOE-e4 gene is similar in males and females. However, there a disproportionate rate women (two-thirds) compared men. Mayeda et al. (2020) found that who worked for pay during early adulthood midlife, whether married or unmarried, had slower memory decline later life did not work pay. Although has been much research on association between type paid environment dementia; instance, complexity, job control, strain, little includes unpaid ascertaining its effect neurocognitive functioning life. This study aims find interaction predicting (operationalized as ADAS13 total score at baseline) women. Method A two-way ANOVA was performed using data initial visit from Disease Neuroimaging Initiative (ADNI) database 340 female participants. Result There were significant main effects ADAS-Cog-13 (F (2,334) = 4.697, p .010) well (1,334) 5.450, .020). 215.725, .091). Conclusion are independently higher scores (Alzheimer’s Assessment Scale) no